Chiphunzitso
Harry Cretefelter ndi dokotala waku America yemwe amakambidwa kafukufuku wochitidwa mu gawo la Endocrininology. Adokotala anali kufunafuna njira zamankhwala zomwe zingathandize kuthana ndi uchidakwa, ndipo ndinayamba kutsegula kupatuka kwapadera chifukwa cha ma chromosomes m'thupi la munthu. Matendawa amatchedwa klinfelter syndrome.Ubwana ndi Unyamata
Harry anabadwa pa Marichi 20, 1912 mumzinda wa Baltimore, komwe kunali ku Maryland. Makolo a Harry ndi Elizabeti Clanielter adadzetsa ana ena atatu. Mankhwala amtsogolo adalandira maphunziro apamwamba kwambiri. Mu 1937 anayamba kumaliza maphunziro a a Jones Honekins University ku kwawo.
Mankhwala acicress Kreenferter Jr. adayamba mu 1941 ngati wothandizira albright. M'zaka zingapo, mnyamata wina amagwira ntchito kuchipatala cha massachusetts.
Kuyambira mu 1943 mpaka 1946, Harry anali kugwira ntchito yankhondo, kenako n'kubwereranso ku Baltimore, komwe adachitira odwala odwala. Anawaphunzitsa sukulu ya zamankhwala, komanso kafukufuku woyesedwa m'munda wa rheumatogy ndi endocrinogy.
Moyo Wanu
Harry Klinfelter adagwira gawo lofunikira pakufotokozera za matenda a chibadwa, koma osadziwika za mbiri ya adokono. Chisangalalo M'moyo Wanu Wasayansi wapeza muukwati ndi Elaine Konlanferter. Ukwati unachitika mu 1943 ku Missouri. Elaine anali nzika zachikhalidwe. Mkaziyo anapatsa Harry atatu ana.Nchito
Kuyamba kuphunzira kupatuka koopsa ndi endocrinologinaloginaloginaloginaloginalol albright kubwerera mu 1941, Chrisffelter adapanga gulu la amuna asanu ndi anayi. Kusanthula kwa odwala kunawonetsa kupatuka zingapo. Mwa iwo, gynecomastia, spermatogeneis ndi voliyumu yochulukirapo ya mahomoni a mahomoni.
Dokotalayo ananena kuti chifukwa cha matendawa ndi vuto la endocrine, koma kale mu 1959 chigamulochi chidachitika. Zomwe zimayambitsa kupatuka kuyambira nthawi imeneyo sizikuwoneka ngati mahomoni, koma ma chromosomes.
Zina mwazizindikiro za syndrome, zomwe zimaphunzira kalambayo, ndiye kukula kochepa kwa testicy. Mu 1942, izi ndi zina mwazizindikiro zotchulidwa m'nkhaniyali pa "magazini yazachipatala chagolical". Kuyambira pano, vutoli linayamba kuitanidwa kulemekeza wofufuzayo.
Malinga ndi adotolo, zinali zotheka kuzindikira matenda oyambira. Pa nthawi yoyang'aniridwa, yomwe anyamata anachitidwa, iye adawona mawonekedwe a phydiology yawo. Nthawi zambiri, matendawa adapezeka mwa anyamata akuluakulu omwe ali ndi zachiwiri zogonana komanso zomwe zimagwira ntchito mwachidwi. Pambuyo pake, zidawululidwa kuti nthawi zonse gynecostia sizikhala chizindikiro chotsatira cha Clanilter Syndrome.
Pambuyo pa zaka 14 pambuyo pa maphunziro oyamba, zidawonekeratu kuti odwala omwe ali ndi endocrine adalipo 47 ma christosomes 47. Adapeza zowonjezera x, kapena gawo lomwe kuphatikiza kwa XXY kunalipo. Chizolowezi chake ndi chromosome imodzi kapena mtundu wina. Chifukwa chake, kuchuluka kwa karbatypes kuwonekera, komwe kumasiyana kwambiri. Zabwino kwa chromatin zimatanthauzanso kuchuluka kwa zizindikilo zomwe zimapezeka pakuzindikira za clanfelther syndrome. Odwala omwe ali ndi chidziwitso chotere amavutika ndi kusabereka.
Vuto lodziwika ndi Harry Cretefelter limaphatikizidwa pamndandanda wa ma genetics otchuka. Matenda amakhudza 0,2% ya amuna padziko lapansi. Kuphatikiza apo, matenda oyamba ndi endocrine amawerengedwa kuti nthawi zambiri amapezeka pambuyo pa matenda ashuga komanso hypecfunction ya chithokomiro cha chithokomiro.
Makhalidwe omwe adakwiyitsidwa ndi matendawa sanatengeredwe, choncho ngati pali mwana m'modzi m'banjamo matendawa, sizingachitike. Neuch nthawi zambiri zimakhala ndi zizindikiro zodziwikiratu. Ngakhale odwala ena adalemba m'lifupi mwake m'chiuno, tsitsi laling'ono lili m'thupi ndi chifuwa chokulirapo. Nthawi zina, mavuto omwe amaphunzira kapena zolankhula. Kuti mudziwe kukhalapo kwa matendawa mwa makanda kapena atsopano, monga momwe zimawonekera pakutha msinkhu. Koma pali mwayi woyesa mokha mpaka mwana akuwonekera.
Harry Clainfelter akufuna kupereka mankhwalawa a zaka za testosterone, zomwe zimathandizira chitukuko cha kugonana. Mukamagwiritsa ntchito pakutha msinkhu, kuthekera kumatheka ndikubweretsa thupi kuti lizikula bwino. Sizingatheke kuchiritsa matenda mpaka kumapeto, popeza kuphwanya kwa majini sizosagwirizana. Koma muchepetse zizindikiro ndikusunga munthu kuchokera ku zovuta. Pamaso pa matendawa, chifukwa cha kutenga, kumathandizanso kuti mwandigwiritse ntchito.
Imfa
Harry Klinfelter anamwalira pa February 20, 1990. Choyambitsa kufa kwa dokotala sawululidwa, koma mwina adalumikizidwa ndi ukalamba wa munthu yemwe wamwalira zaka 77. Popeza adapereka ntchito yophunzira umodzi mwa kupatuka kotchuka kwambiri kwa manema m'zaka za zana la 20, adotolo adapereka gawo lalikulu pakukula kwa sayansi. Masiku ano, chithunzi cha endocrinologist chimafalitsa m'mabuku akuyunivesite.